Bioorganic and medicinal Chemistry

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials

Organic Chemistry / Drug Discovery / Animals / Drug Resistance / Plasmodium falciparum / Antimalarials / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antimalarials / Bioorganic and medicinal Chemistry / Structure activity Relationship

In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity

Organic Chemistry / Medicinal Chemistry / Obesity / Pharmacokinetics / Pharmaceutical Chemistry / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity

Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification

Organic Chemistry / Pharmacokinetics / In Vitro / Humans / Animals / Drug Design / Acetylcholine / Bioavailability / Microdialysis / In Vivo / Rats / Rat / Cholinergic Receptor / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Chemical Synthesis / Area Under Curve / Benzamides / Drug Design / Acetylcholine / Bioavailability / Microdialysis / In Vivo / Rats / Rat / Cholinergic Receptor / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Chemical Synthesis / Area Under Curve / Benzamides

Benzylidene ketal derivatives as M2 muscarinic receptor antagonists

Organic Chemistry / Bioorganic and medicinal Chemistry / Muscarinic Receptor

New vasorelaxant indole alkaloids, villocarines A–D from Uncaria villosa

Organic Chemistry / Calcium / Pharmacognosy / Magnetic Resonance Spectroscopy / Structural Analysis / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves

Acyl sulfonamide anti-proliferatives. Part 2: Activity of heterocyclic sulfonamide derivatives

Organic Chemistry / Humans / Bioorganic and medicinal Chemistry / Cell Proliferation / Structure activity Relationship / Vascular Endothelial Growth Factor

Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties

Organic Chemistry / Kinetics / Pharmaceutical Chemistry / Humans / Drug Design / Peptides / Enzyme Inhibition / Gonadotropin Releasing Hormone / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ions / Molecular Structure / Peptides / Enzyme Inhibition / Gonadotropin Releasing Hormone / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ions / Molecular Structure

Synthesis of racemic 2-phosphonomethyl-1,3-dioxolane nucleoside analogues as potential antiviral agents

Organic Chemistry / Bioorganic and medicinal Chemistry

Design, synthesis, and in vitro activities of benzamide-core glycoprotein IIb/IIIa antagonists: 2, 3-diaminopropionic acid derivatives as surrogates of aspartic acid

Organic Chemistry / Magnetic Resonance Spectroscopy / Humans / Liver / Animals / P-glycoprotein / D-Aspartic Acid / Platelet Rich Plasma / Swine / Benzoic Acid / Alkylation / Esterases / Alanine / Bioorganic and medicinal Chemistry / Structure activity Relationship / Carbamates / Benzamides / Piperidines / P-glycoprotein / D-Aspartic Acid / Platelet Rich Plasma / Swine / Benzoic Acid / Alkylation / Esterases / Alanine / Bioorganic and medicinal Chemistry / Structure activity Relationship / Carbamates / Benzamides / Piperidines

N, N-Dialkyl-4-[(8-Azabicyclo [3.2. 1]-Oct-3-Ylidene) Phenylmethyl] Benzamides, Potent, Selective [Delta] Opioid Agonists

Organic Chemistry / Bioorganic and medicinal Chemistry / Opioid Receptor / Structure activity Relationship / Benzamides

N-(Sulfonamido)alkyl[tetrahydro-1 H-benzo[ e]indol-2-yl]amines: potent antagonists of human neuropeptide Y Y5 receptor

Organic Chemistry / Macromolecular X-Ray Crystallography / Humans / Neuropeptide Y / Bioorganic and medicinal Chemistry / Molecular Structure

Acyl sulfonamide anti-proliferatives. Part 2: Activity of heterocyclic sulfonamide derivatives

Organic Chemistry / Humans / Bioorganic and medicinal Chemistry / Cell Proliferation / Structure activity Relationship / Vascular Endothelial Growth Factor

1
2
3
4
5
6
7
8
9
»

Copyright © 2017 DATOSPDF Inc.